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Transforming biology from empirical to predictive

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Machine intelligence makes biochemical omics broadly accessible to the life sciences

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The Challenge

Despite advances in sequence-based omics, the success rate of life science pipeline R&D remains low. Sequence data alone miss the key drivers of biological variation needed to predict pipeline outcome.

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More Explanatory Power

Biochemical omics explain orders of magnitude more biological variation than sequence but have been broadly inaccessible for life sciences applications due to the limitations of conventional data analysis.

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Large Spectral Model

AI trained on billions of small molecule, lipid, peptide and protein spectra across millions of biological contexts extracts hidden predictive power from your omic data to bend the pipeline R&D success curve in your favor.

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Use cases for your science

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Asset & Target Discovery

Generatively discover new molecules, variants, and populations. Elucidate novel modes of action via quantitative untargeted biochemical annotation and latent space biomarkers 


Toxicology & Safety

Derisk candidates earlier via predictive toxicity, immunogenicity and off-target effects. Identify reactive intermediates, adducts, and biotransformation products in complex matrices.

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Clinical Development

Predict clinical phenotypes, efficacy and responder effects. Derisk subject stratification, donor selection, and support MIST assessment with broad and quantitative biochemical annotation.


CMC & Biomanufacturing

Predictive cell line development, process optimization, early detection of batch excursion. Accelerate bioprocess metabolic engineering and generatively optimize titer and productivity.

Build the future of predictive biology with us

Partner with Matterworks to apply LSM machine intelligence to your most challenging and high-value R&D problems across the discovery, development and biomanufacturing sciences.
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All powered by Pyxis

Meet your AI predictive biologist

Our cloud-based AI is where every engagement comes to life. Pyxis guides your analysis and our predictive omics assistant helps you build models that directly interpret data to biological insights. Your proprietary data, models and results remain yours.

We have made untargeted biochemical annotation capabilities open for anyone to try. Sign up now and run your own data to get a taste of how machine intelligence can transform your life science pipeline R&D.

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Check out our latest insights

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Case Study: Metabolic Signatures in Guillain-Barré Syndrome (Coming Soon)
Case Study: Metabolic Signatures in Guillain-Barré Syndrome (Coming Soon)

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Introducing Pyxis (Coming Soon)
Introducing Pyxis (Coming Soon)

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Introducing LSM-MS2
Introducing LSM-MS2

Our new best-in-class spectral identification model for raw MS2 data.

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Read All Insights
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STANDARD

Explore Pyxis on
your data

Start Now

  • Immediate platform access
  • Initial analysis credits for introductory model: untargeted biochemical annotation 
  • Molecular structure and relative quantitation from raw MS data
  • Self-service onboarding
Get Started With Pyxis

Immediate platform access, no credit card required.

ENTERPRISE

For teams &
organizations

Custom

  • Dedicated onboarding & training
  • Direct phenotype prediction from your application-labeled datasets
  • Access to broadest and most quantitative biochemical annotation model, including concentration determination for untargeted biomolecules
  • Integration support

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